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Genitalia & Reproductive Organ Transplants

Timble2

Imaginary Person
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There seems to have been run of stories on human reproduction these last few days....

http://news.bbc.co.uk/1/hi/health/3035628.stm

Womb transplant baby 'within three years'

by Martin Hutchinson
BBC News Online health staff in Madrid

The end result of a womb transplant?

Scientists claim that the first human baby could be born from a transplanted womb within three years.
Animal experiments have dismissed many of the concerns that womb transplants could not produce healthy babies.

The Swedish expert behind the research says that one of the best candidates to be an organ donor would be the patient's own mother - raising the prospect of carrying your children in the same womb that carried you.

He says that it may even be technically possible one day to transplant a womb into a man, and use hormone injections to allow a pregnancy to succeed.

However, it would be the first organ transplant which is not needed to cure a life-threatening illness, and there is likely to be a debate over whether such major surgery - and powerful immune-suppressing drugs - can be justified................

It's also at:
http://www.newscientist.com/news/news.jsp?id=ns99993892
 
Of course two men would make better genetic parents than two women- men have got x and y chromosomes, so could produce boys or girls, while parthenogenic women would only produce females.

Ach- eventually most people will be born from artificial wombs, like in Brave New World...
I could never see the problem with that society- at least people were happy
:)
 
A friend of mine was clearing out loads of old newspapers from the house of a recently deceased old lady. Why she kept them, we have no idea. I was directed to a particular newspaper from 1973 and an article about a woman born without a vagina and who had, well, I can hardly bring myself to tell you....... HER MOTHER'S VAG TRANSPLANTED WHERE HERS SHOULD HAVE BEEN! There, I said it!

Apparently, the Mother wanted to save the daughters marriage by gifting the blushing couple with her 2nd hand vag. I put the article on my fotolog site if anyone's interested. I can't get over it, I really can't.....

http://www.fotolog.net/sketty/?photo_id=5723559
 
That is the creepiest thing I ever heard..... :cross eye
 
p.younger said:
Wasn't in the Sunday sport by any chance.

I was wondering about the newspaper it was in because it doesn't sound likely but the font looks like a more upmarket newspaper.

[edit: And as odd as it sounds:

First vaginal transplant

A woman aged twenty-one in Salonica was reported as having a boyfriend, two years after receiving a vagina transplant from her mother aged fifty. A professor at the city's university was reported as saying there had been no signs of tissue rejection. The woman's previous deformity had led to the dissolution of her first marriage. The operation to equip her with a new genital tract was apparently successful ("Guardian", 5/3/73).

From The Illustrated Book of Sexual Records.
© 1974, 1982, 1997-2001 G.L. Simons

http://www.world-sex-records.com/sex-014.htm

There are some second copies of the book available through Amazon:

http://www.amazon.co.uk/exec/obidos/ASIN/0517448998/

if you were wondering if it was a real book ;)

Anyway good find - rescued that one from the wastebin of history!! ]

Emps
 
live donations always make me cringe for some illogical reason......

:(

Kath
 
I don't believe it.

They had the technology back in 71 to have created her one from skin grafts and/or bowel tissue, I don't see why they'd have gone to the trouble of cutting one out of a healthy person.


Edit: It seems this appeared in The Illustrated Book Of Sexual Records in 1974, which refers to a newspaper article in the "Guardian".

http://www.world-sex-records.com/sex-014.htm

Maybe it is true after all. Damn creepy though...
 
BlackRiverFalls said:
I don't believe it.

They had the technology back in 71 to have created her one from skin grafts and/or bowel tissue, I don't see why they'd have gone to the trouble of cutting one out of a healthy person.

That kind of technology was not that advanced in Greece in those days - it was simpler for them to do a transplant.
 
actualy if you look , they all look "used", sort of second hand..I mean would you buy a car that looked that knackered????? :rolleyes:P.S. i guess that would make the "lucky" husband a mother F^*ker
 
naSTEe said:
i guess that would make the "lucky" husband a mother F^*ker

:rofl:

When you think about it, it's kind of odd getting a hole transplanted. Especially when it's one that you came out of 21 years ago. :cross eye
 
Breezilla said:
When you think about it, it's kind of odd getting a hole transplanted. Especially when it's one that you came out of 21 years ago. :cross eye

Good point - you'd be like some kind of reproductive Mobius Loop. You wouldn't know if you were coming or going (well someone had to say it ;) ).

Emps
 
Oh for the love of the Wee Man :err:

I agree - that is disturbing on all kinds of planes at once - I really, really wish I hadn't read that.

Still, smashing post, Sketty :)
 
Heh heh (she chuckled), I'm glad you enjoyed it. I wondered at the 'hole' transplant bit myself. I mean, how would one transplant a hole? Actually, scrap that - I really don't want to know.

I guess it solves the question of what you get for the couple who has everything. In my sick, fevered mind I imagined them opening up a beautifully wrapped box containing something akin to a large hairy hula hoop......
 
Penis Transplant

http://www.dailymail.co.uk/pages/live/a ... ge_id=1770

An accident victim has become the first person to have a penis transplant.

The 44-year-old man was given the 4in organ from a braindead patient half his age in a complex 15 hour operation.

But the organ had to be removed just 14 days later due to "a severe psychological problem with the recipient and his wife".

Transplant expert Professor Andrew George, from Imperial College London, said it was unclear if the man would have been able to perform sexually with the donated penis.

"Doing a penis transplant should be no more complex than anything else," he said. "But it takes time for nerve sensations to kick in."

Top French surgeon Dr Jean-Michel Dubernard, who performed the world's first face transplant on a woman who had been attacked by a dog this year, said psychological consequences were a serious issue for many patients.

"Psychological consequences of hand and face allografts show that it is not so easy to see permanently a dead person's hands, nor is it easy to look in a mirror to see a dead person's face," he wrote in the journal.

"Clearly, in the Chinese case the failure at a very early stage was first psychological. It involved the recipient's wife and raised many questions."

During the operation, carried out by surgeons in China, nerve fibres and tiny blood vessels were stitched to the donated penis.

It also had to be connected to the urethra - the tube that empties the bladder.

The patient was then given drugs to stop his immune system rejecting the new penis.

Surgical teams claimed the operation was a sucess. Tests showed it had a rich blood supply and after just ten days, the man was able to urinate through it without the use of a catheter, according to a report in the European Journal of Urology.

The proceedure is regarded as a major step forward in transplant surgery and brings new hope to men whose sex organs are damaged beyond repair in accidents or birth defects.

Earlier this year, French surgeons transplanted a dead woman's face on to a dog-attack victim.

Two years ago an Austrian team transplanted a human tongue into a patient with jaw cancer.

Doctors have reattached male organs before, but this is the first time they have completed a penis transplant.


(C) Daily Mail 06

(I hope it's ok, to place under the face transplant thread?)
 
But the organ had to be removed just 14 days later due to "a severe psychological problem with the recipient and his wife".

You think a rag like the DM would clarify on this fastinating aspect....
 
Kondoru said:
But the organ had to be removed just 14 days later due to "a severe psychological problem with the recipient and his wife".

You think a rag like the DM would clarify on this fastinating aspect....

"Yeah but love the nail might be different, but the hammer is the same"
 
I mean, what kind of heartless woman would complain because her husband had a strange penis??

Or maybe she was led to believe it would work and it didnt??
 
Kondoru said:
But is it ethical to reveal the name of the donor? I dont think that would be allowed over here.

Shouldn't that be dependent upon the wishes of the donor's family?
 
Man rejects first penis transplant
Ian Sample, science correspondent
Monday September 18, 2006
The Guardian

Chinese surgeons have performed the world's first penis transplant on a man whose organ was damaged beyond repair in an accident this year. The incident left the man with a 1cm-long stump with which he was unable to urinate or have sexual intercourse. "His quality of life was affected severely," said Dr Weilie Hu, a surgeon at Guangzhou General Hospital.
Doctors spent 15 hours attaching a 10cm penis to the 44-year-old patient after the parents of a brain-dead man half his age agreed to donate their son's organ.

The procedure, described in a case study due to appear in the journal European Urology next month, represents a big leap forward in transplant surgery; it required complex microsurgery to connect nerves and tiny blood vessels.
The surgical team claims the operation was a success. After 10 days, tests revealed the organ had a rich blood supply and the man was able to urinate normally.

Doctors have previously succeeded in reuniting men with their sexual organs after traumatic accidents or attacks, but the Guangzhou operation is the first in which a donor penis has successfully been attached to another man.

Although the operation was a surgical success, surgeons said they had to remove the penis two weeks later. "Because of a severe psychological problem of the recipient and his wife, the transplanted penis regretfully had to be cut off," Dr Hu said. An examination of the organ showed no signs of it being rejected by the body.

Jean-Michel Dubernard, the French surgeon who performed the world's first face transplant on a woman who had been attacked by a dog this year, said psychological factors were a serious issue for many patients receiving certain "allografts", or organs from donors. "Psychological consequences of hand and face allografts show that it is not so easy to use and see permanently a dead person's hands, nor is it easy to look in a mirror to see a dead person's face," he wrote in the journal. "Clearly, in the Chinese case the failure at a very early stage was first psychological. It involved the recipient's wife and raised many questions."

In 2001, surgeons were forced to amputate the world's first transplanted hand from Clint Hallam, a 50-year-old New Zealander, who said he wanted the "hideous and withered" hand removed because he had become "mentally detached" from it. The original transplant was conducted by Prof Dubernard's team at the Edouard Herriot Hospital in Lyons, who have since performed the world's first double arm transplant.

Andrew George, a transplant expert at Imperial College, London, said: "Doing a penis transplant should be no more complex than anything else. But it takes time for nerve sensations to kick in and it's not clear whether the patient would ever be able to have sex with it. The question is whether it's right to be doing a transplant for what may be seen as cosmetic reasons."

http://www.guardian.co.uk/china/story/0 ... 17,00.html
Erm, I've not heard what men do with their penis described as 'cosmetic' before! :D
 
What seems to have happened here is that the man was able to accept the penis as 'his', whereas his wife was not.

Cosmetic, hmmm, you'd be surprised what stories you hear! :lol:
 
Haha, I heard about the penis transplant on a talk show on the radio and thought it was a joke because of the people chatting being humourous about.

They were saying the wife rejected it thinking it wasn't big enough.
 
A bit more explanation of what happened with the aforementioned 2006 transplant that failed is provided in this new item - a report that the first complete penis / scrotum transplant is doing as well as hoped a year after the surgery. This article also cites 3 other transplants done since we last discussed this subject here.
World's First Penis And Scrotum Transplant Is Fully Functional Over One Year On

Over a year since the history-making operation, the recipient of the world's first total penis and scrotum transplant – an injured veteran of the US Armed Forces – is "feeling whole" again and recovering well, doctors report in a case note on the pioneering procedure.

The man, who remains anonymous, was on patrol with his squad in Afghanistan when Taliban fighters ambushed them. As he went to give first aid to another soldier, he stepped on an improvised explosive device hidden on the road. In an instant, the blast took away much of the lower half of his body.

... "I remember thinking a quick thought: 'This isn't good.'"

It wasn't. In the sudden explosion, the soldier lost most of his legs, as well as his genitals and part of his abdomen. This was back in 2010.

At the time, there had only ever been one reported penis transplant, performed in 2006 on a patient in Guangzhou, China; as far as precursors go, it wasn't exactly promising. Complications set in early, and the man's body began to reject the organ, which showed signs of necrosis, possibly due to inadequate blood supply.

There were also psychological issues – including reported objections from the patient's wife – and the graft was removed only a fortnight later.

Nonetheless, reconstructive surgery specialists at Johns Hopkins Hospital were confident their soldier patient, whom they first met in 2013, would make a good candidate for transplant surgery – although it took five years of preparation (including extensive experimentation on cadavers) before they got a chance to try, once a suitable organ from a deceased donor finally became available.

During that long interim, three successful penis transplants had been completed: two in South Africa, both on patients who experienced penile loss due to infections stemming from circumcision; and one involving a man in the US, who had the surgery after a partial penectomy from penile cancer.

Yet none of those patients had lost as much as the soldier. His operation would be particularly ambitious, involving the transplant of a single piece of tissue encompassing penis, scrotum, and lower abdominal wall all together – something doctors had never attempted before.

In total, the entire transplant weighed nearly five pounds (over two kilograms), and measured 10 by 11 inches (roughly 25 cm).

Despite the challenges – which involved stitching together hundreds of tiny blood vessels only a millimetre or two wide under a powerful microscope – a 14-hour operation performed by 11 different surgeons was a success.

Even more significantly, over a year on from this world-first transplant, the medical team reports the patient is recovering well, with the organ and its reestablished nerve connections functioning about as well as could be hoped for. ...

FULL STORY (With More Details On The Recovered Functionality):

https://www.sciencealert.com/world-...tum-transplant-is-a-total-success-one-year-on
 
There seems to have been run of stories on human reproduction these last few days....

http://news.bbc.co.uk/1/hi/health/3035628.stm



It's also at:
http://www.newscientist.com/news/news.jsp?id=ns99993892


Well, it did happen! There have been 11 babies born from 39 attempts at live womb transplants as of December 2018, and according to this story from the BBC at https://www.bbc.co.uk/news/health-46438396

"A healthy baby girl has been born using a womb transplanted from a dead person.

The 10-hour transplant operation - and later fertility treatment - took place in São Paulo, Brazil, in 2016. The mother, 32, was born without a womb...
... In this case, reported in The Lancet, the womb donor was a mother of three in her mid-40s who died from bleeding on the brain.

The recipient had Mayer-Rokitansky-Küster-Hauser syndrome, which affects about one in every 4,500 women and results in the vagina and uterus (womb) failing to form properly. However, her ovaries were fine. And doctors were able to remove eggs, fertilise them with the father-to-be's sperm and freeze them.

The woman was given drugs that weakened her immune system to prevent her body attacking and rejecting the transplant. The 10-hour transplant operation - and later fertility treatment - took place in São Paulo, Brazil, in 2016 and about six weeks later, she started having periods.

After seven months, the fertilised eggs were implanted. And, after a normal pregnancy, a 6lb (2.5kg) baby was delivered by Caesarean section on 15 December 2017..."


I remember reading that the uterus transplants were normally semi-temporary, due to health issues with immunosuppressant drugs, and that after a child was born the uterus was often removed at a later date.

Infertility in itself is such an emotionally painful condition and if there is a solution because of altruistic living/dead donors then I'd not deny the women the chance to give birth. It's not exactly a common procedure, either.
 
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