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The Slow Loris: The Sole Primate With A Venomous Bite

lordmongrove

Justified & Ancient
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May 30, 2009
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Slow loris imitates cobras

popsci.com/article/science/v ... f=obinsite
This link now requires a login to access the article. Another article which appears to be the same thing is similarly firewalled at the Business Insider website.

Cute little fuzzy bundles of venom.
 
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This Smithsonian web article from the same timeframe (October 2014) apparently covers the same general subject matter.
The Only Primate With a Toxic Bite Might Have Evolved to Mimic Cobras

Slow lorises have snake-like markings, postures and a hiss that all resemble the speckled cobra

Slow lorises are known for their cuteness. Nocturnal primates that live in Southeast Asia, the lorises have round heads, big eyes, fuzzy fur, and—if they lick a gland under their arms and combine the secretion there with their saliva—a less-than-adorable toxic bite.

That bite, combined with a hiss-like vocalization, sinuous movements, and a distinctive defensive posture in which the loris raises its arms above its head, make the primate look remarkably like a spectacled cobra ready to strike. Which raises the question: Did the loris evolve to mimic poisonous snakes?

Yes, argues a paper published in the Journal of Venomous Animals and Toxins including Tropical Diseases last year. To back up this idea, the researchers noted that cobras and slow lorises lived and migrated through the same part of Asia about eight million years ago. Quick climate changes in the region stripped the Malay Peninsula of tropical forests and replaced them with drier woodlands. That opened up the loris’s habitat more and could have provided pressure to mimic a poisonous snake.

As a result, the researchers suggest, the loris’s markings resemble those of the snake, especially if the animal is encountered in the dusk of twilight, as one naturalist found out. ...

"Few people have ever researched loris venom, so few hypotheses have been generated," lead author Anna Nekaris, the director of Oxford Brookes University's Little Fireface Project, told mongabay.com. "We are hoping that people would like to test the cobra hypothesis—it does have some scientific basis. But of course there are other hypotheses."

For instance, the primates are called slow lorises for a reason. Toxin might help them subdue the birds, bats, lizards and even tarsiers they are known to eat. But observations suggest that lorises can take down these animals and eat them fairly quickly—no paralysis needed.

Maybe the toxin helps protect against predators and parasites. Or, like the male platypus’s spur, it could have evolved to be used as a weapon during fights with other lorises. None of these explain the snake-like movements (an extra vertebrate in their spine gives lorises this ability), hiss and markings, but they certainly could have sped along the evolution of a poisonous bite.
FULL STORY: https://www.smithsonianmag.com/smar...te-might-have-evolved-mimic-cobras-180952926/
 
Newly published research indicates slow lorises aren't just similar to cobras. It turns out some components in their venom are identical to the chemical agents in cat saliva that are central to cat allergies.
The World's Only Venomous Primate Could Explain Why Humans Are Allergic to Cats

For those with a severe cat allergy, any location that harbours a pet feline can become a toxic no-go zone. Research on another tragically cute mammal now suggests this might be no accident of nature – cats really are trying to keep us away.

A study on the world's only known example of a venomous primate has found a surprising similarity between a key protein in its armpit glands and the allergen found in cats, raising the suggestion that if one evolved as a defensive weapon, so might the other.

It's a finding that not only puts cat allergies into a new context, but could lead to treatments for those suffering the effects of an unpleasant encounter with either animal.

Slow lorises (Nycticebus sp.) are several species of primate commonly found in the wilds of South and Southeast Asia. Looking at one, you'd swear it was dreamed up in a Hasbro toy workshop for toddlers.

But don't let the looks fool you. Inside the loris's mouth are rows of tiny, razor-sharp teeth used to both tear into small prey and keep predators and competitors at bay.

As if a bite isn't enough, when threatened, the fluff monsters put their hands up and lick the glands tucked away in their armpits, dosing their spit with a rich array of compounds fine-tuned to help transform a tiny cut into a festering hole of dead flesh.

"Generally slow lorises use their venom to fight with other slow lorises, causing very slow-to-heal wounds," says biologist Bryan Fry from the University of Queensland in Australia.

"But, when humans are bitten, the victim will display symptoms as if they're going into allergic shock."

Those symptoms can include difficulty breathing, blood in the urine, extreme pain, and - in the worst cases - anaphylactic shock.

The secretions responsible for the toxic effects of the animal's bite are known to include more than two hundred aromatic compounds, many of which have already been characterised.

But among them are a bunch of proteins which still pose some mystery, and it's these chemicals that Fry and his team sequenced to learn more about their origins and toxicity.

Surprisingly, the proteins weren't entirely new to science. In fact, many of us are painfully familiar with them already.

"We analysed the DNA sequence of the protein in slow loris venom, discovering that it's virtually identical to the allergenic protein on cats," says Fry.

"Cats secrete and coat themselves with this protein, and that's what you react to if you're allergic to them." ...
FULL STORY: https://www.sciencealert.com/toxins...d-tell-us-why-many-of-us-are-allergic-to-cats
 
Look what I found

Unbelievably cute baby Loris at the end. The presenter's not half bad as well.

 
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