Oh, it's obvious that a flash has been used, but by itself that doesn't rule out an infrared film, but if you look at real infrared photos you'll see that skin looks snow white because it reflects infrared light strongly in the spectrum range the film is sensitive to, but in this one the skin is normal looking. It might have been that Warren simply didn't put an infrared filter on his lens.
If you reject Weber as unreliable, why accept the Lutzes as reliable, given that as Joe Nickell notes:
" * The Lutzes could not have found the demonic hoofprint in the snow when they said they did, because weather records showed there had been no snowfall to leave prints in.
* Though the book details extensive damage to the home's doors and hardware, the original locks, doorknobs, and hinges were actually untouched.
* The book and film show police being called to the house, but, Nickell writes, "During the 28-day 'siege' that drove [the Lutz family] from the house, they never once called the police."
http://www.snopes.com/horrors/ghosts/amityville.asp
The spookiness of the photo hinges on whether Warren was correct when he said no one was in the house at the time of the photos - given that the person in the photo appears to be wearing a plaid shirt and glasses, objects which one would be surprised to find have an afterlife, and that the Warrens have been described in another case as:
“My brother ...... along with my family, was manipulated and exploited, something the Warrens were very good at, and along with their author, Gerald Brittle, they concocted a phony story about demons in an attempt to get rich and famous at our expense, and we have the evidence to prove it.”
http://www.mmdnewswire.com/brors-sue-wo ... 347-2.html
It does not seem unreasonable to doubt the stated facts about the photo.